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PUBLICATIONS
2026-05-15
Scott B. Hansen* “Lipid Agonism; the PIP2 Paradigm of ligand gated ion channels” Biochim Biophys Acta (2015) May 1851 (5): 620-628.
2026-05-15
Wang, H., Kulas, J.A., Higginbotham, H., Kovacs, M.A., Ferris, H.A., and Hansen, SB* (2023). Title: Regulation of neuroinflammation by astrocyte-derived cholesterol BioRxiv.
2026-05-15
Scott B. Hansen, Xiao Tao, Roderick MacKinnon “Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2” Nature 2011, 477:495-98
2026-05-15
Hansen SB, Wang, HL, Taylor P, and Sine SM “An Ion-Selectivity Filter in the Extracellular Domain of Cys-loop Receptors Reveals Determinants for Ion Conductance. J Biol Chem. 2008 Dec 26:283(52):36066-70
2026-05-15
Hansen SB and Taylor P “Galanthamine and Non-competitive Inhibitor Binding to ACh-binding Protein: Evidence for a Binding Site on Non--subunit Interfaces of Heteromeric Neuronal Nicotinic Receptors” J. Mol. Biol. 2007 June 369, 895-901
2026-05-15
26. Gao F, Mer G, Tonelli M, Hansen SB, Burghart TP, Taylor P, Sine SM. “Solution NMR of Acetylcholine Binding Protein Reveals ACh-mediated Conformational Change of the C-loop” Mol Pharmacol. 2006 Oct 70(4): 1230-5
2026-05-15
Hibbs RE, Johnson DA, Shi J, Hansen SB, and Taylor P “Structural Dynamics of the -Neurotoxin-Acetylcholine Binding Protein Complex: Hydrodynamic and Fluorescence Anisotropy Decay Analyses” Biochemistry 2005, 44:16602-11
2026-05-15
Hansen SB, Sulzenbacher G, Huxford T, Marchot P, Taylor P, and Bourne Y “Structures of Aplysia AChBP complexes with agonists and antagonists reveal distinctive binding interfaces and conformations” Embo J 2005, 24:3635-46
2026-05-15
Bourne Y, Talley TT, Hansen SB, Taylor P and Marchot P “Crystal structure of a Cbtx-AChBP complex reveals essential interaction between snake -neurotoxins and nicotinic receptors” Embo J 2005, 24: 1512-22
2026-05-15
Gao F, Bren N, Burghardt TP, Hansen SB, Henchman RH, Taylor P, McCammon JA, Sine SM. “Agonist-mediated conformational changes in acetylcholine-binding protein revealed by simulation and intrinsic tryptophan fluorescence” J Biol Chem. 2005 Mar 4;280(9):844
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